Cambio de haloperidol a olanzapina en una muestra de pacientes peruanos esquizofrénicos con extrapiramidalismo

Objective: efficacy and safety of change from haloperidol to olanzapine was evaluated in a sample of homogeneous population of Peruvian schizophrenic patients with extrapyramidal symptoms. Methods: thirty Peruvian patients with schizophrenia (DSM-IV criteria) were changed from haloperidol ≤20 mg/d to olanzapine 10 to 20 mg/d for eight weeks. Potential changes in the extrapyramidal symptoms observed in all the patients at study baseline were evaluated using Simpson Angus Scale (SAS) and Barnes Akathisia Scale (BAS). Brief Psychiatric Rating Scale (BPRS), positive and Artemisa medigraphic en linea