One kind of ibuprofen injectable formulation and preparation method

The present invention relates to an injectable formulation of ibuprofen and its preparation method, and particularly relates to a meglumine ibuprofen injectable preparation and a preparation method of a co-solvent, wherein the molar ratio of meglumine to ibuprofen 0.1 to 2.0: 1. The present invention provides a new and effective method to dissolve ibuprofen, quickly, sufficiently exert the efficacy of ibuprofen, a solution or solution form may be lyophilized powder preparation for injection. Pharmacy stability test, test animal safety, pharmacokinetics test and other tests, the present invention is the injectable formulation of ibuprofen stability, safety and effectiveness of several visits, results show that the injection of ibuprofen strong stability of the formulation compared to the prior art, to better ensure the safety of the drug effective.