Abstract 168: Interim Analysis of the SMART Registry on the Utility of the Penumbra Smart Coil System in Treatment of Intracranial Aneurysms and Malformations

Introduction: Smart Coils are novel generation embolic coils designed with robust shape and multiple transitions of softness to promote dense packing and durable long term occlusion. We report data on the utility of the Penumbra Smart Coil System in treatment of a variety of intracranial vascular lesions such as aneurysms and other abnormalities. Methods: SMART is a prospective, multicenter registry on the benefits of Smart Coils for treatment of cerebral aneurysms and malformations. This interim analysis aims to evaluate data from the initial 250 patients. Procedures must employ ≥75% of the Smart, PC400, or POD coils to meet the registry criteria. Study endpoints include procedural device-related serious adverse events (SAE), and the occlusion status immediately post procedure. Follow-up will be conducted through 1 year. Results: A wide range of presenting lesions were observed in the first 250 consecutive patients enrolled, including aneurysms (87.9%), of which 27.6% were ruptured, arteriovenous malform...