Imaging of localized retinal nerve fiber layer defects in preperimetric glaucoma using spectral-domain optical coherence tomography.

Purpose:To characterize preperimetric retinal nerve fiber layer (RNFL) defects on speckle noise–reduced spectral-domain optical coherence tomography (SD-OCT), and to determine whether detection of preperimetric RNFL defects can be improved by speckle noise reduction.Patients and Methods:Thirty-two e