Improved CMCase production by Spicellum roseum

CMCase enzyme production by Spicellum roseum NRRL 13104 was increased from 2.1 to 3.4 mg reducing sugar (RS) h−1· ml−1 broth in four experimental stages: (1) selection of important types of ingredients, (2) confirmation of their importance, (3) comparison of sources of the ingredient and (4) partial evaluation of concentrations.