DIVALENT CATIONS LEVELS CHANGES IN NEPHROTIC SYNDROME

nary excretion of cations in pediatric patients with acute urinary infections. We also evalua ted malondyaldehide (MDA) and total antioxidant capacity (TAC) plasma levels. Results: The obtained results show that serum levels of Ca, Cu, Zn are decreased in patients with acute urinary infections compared with a control group of healthy children, while urinary excretion of Cu and Zn there were higher in group study compared with control group. There are no significant differences of the serum magnesium concentration. Increased plasma MDA levels and decreased plasma TAC, Cu and Zn concentrations indicate an increased oxidative stress in patients with acute renal diseases. Conclusions: Our preliminary data show that in some acute urinary conditions, such as lower urinary tract infection and pyelonephr itis, appear disturbances of plasma and urinary concentrations of divalent cations. We consi der that trace elements should be measured routinely in children with renal disorders. Key words: ZINC, COPPER, MAGNESIUM, NEPHROTIC SYNDROME