Cardiac resynchronization therapy with wireless left ventricular endocardial pacing: is this the direction to go?

Cardiac resynchronization therapy (CRT) nowadays is an important part of invasive heart failure therapy (1). Furthermore, it gains increasing recognition for anti-bradycardia pacemaker indications with an expected high burden of ventricular pacing by reducing cardiac remodeling (2). With a considerable number of CRT implantations worldwide, the impact of the recent clinical evaluation of wireless endocardial left ventricular (LV) pacing with a novel wireless cardiac resynchronization system (WiSE-CRT, EBR Systems, Sunnyvale, California, USA) by Reddy et al . 2017 should be further debated (3).