Predictive value of maternal C-reactive protein at admission for latency period in preterm premature rupture of the membranes patients

목적: C-reactive protein (CRP) is a serum marker for diagnosis of acute inflammation and/ or infection and has been examined among patients with preterm premature rupture of the membranes (PPROM). In our study, the predictive value of maternal CRP at admission for duration of the latency period in PPROM patients has been evaluated. 방법: This was a retrospective study of 72 consecutive singleton pregnancies diagnosed with PPROM from 24 to 34weeks, delivered at Inje University College of Medicine Ilsan-Paik Hospital. Maternal CRP was assessed at admission. Duration of Latency period was categorized by days of latency (2days, 7days, 14days, 21days, 28days). Receiver operating characteristic (ROC) curves were employed to evaluate the predictive value of maternal CRP for duration of the latency period in PPROM patients. 결과: ROC curves showed that maternal CRP at admission in latency period of 14days (area under the curve(AUC) : 0.745, p=0.004), 21days (AUC : 0.752, p=0.006) and 28days (AUC : 0.716, p=0.027) are predictive of latency period (Table 1). 결론: Maternal serum CRP (≤0.3mg/dL) at admission in PPROM patients may be predictive value in latency period of above 14days.