AB0577 Sleep Quality in Behcet's Disease Is Associated with Disease Activity, Depression, and Quality of Life in Korean Populations

Background Behcet9s disease is a chronic, systemic vasculitis that can involve all sizes of blood vessels. Those complicated symptoms lead to the patient9s impairment of life quality as well as psychological problems. Sleep disturbance is one of the most particular concerns in patients with Behcet9s disease. It has been known that the disease activity of rheumatoid arthritis and ankylosing spondylosis is associated with the sleep quality. However, studies about the sleep quality of patients with Behcet9s disease in Korean population are limited. Objectives The purpose of this study was to find out the effects of sleep quality on Behcet9s disease in Korean population. We also investigated the relationship between depression, quality of life, other clinical findings of Behcet9s. Methods The study was performed by cross-sectional design in two tertiary hospitals. We met one hundred patients with Behcet9s disease, surveyed them face-to-face and conducted the chart review for more clinical informations. Sleep quality was assessed by the Korean version of Pittsburgh sleep quality index (PSQI). Disease activity of Behcet9s disease was evaluated by Behcet9s disease current activity form (BDCAF). Depression was assessed by the Korean version of Beck depression inventory second edition (BDI-2). Quality of life was assessed by the Korean version of the Leeds Behcet9s Disease Quality of Life Measure (BDQoL). Results Among 100 patients, median age was 51 [44.5–56.0] years, median disease duration was 77.5 [24.0–136.0] months and 31% were male. Those who met the diagnostic critera of fibromyalgia were 28 patients. The frequency of poor sleep quality (PSQI >5) was 67%. Patients with poor sleep quality tend to have higher BDI2, BDCAF and pain VAS score (P Conclusions The low quality of sleep is associated with disease activity, depression and quality of life in Korean patients with Behcet9s disease. We expect better disease control will improve the sleep quality. References Tascilar NF, Tekin NS, Ankarali H, Sezer T, Atik L, Emre U, Duysak S, Cinar F. J Sleep Res 2012;21:281–8. Melikoglu MA, Melikoglu M. Rheumatol Int 2010;30:941–6. Disclosure of Interest None declared