Quantification of vanillylmandelic acid, homovanillic acid and 5-hydroxyindoleacetic acid in urine using a dilute-and-shoot and ultra-high pressure liquid chromatography tandem mass spectrometry method

Eric Grouzmann,Catherine Centeno,Philippe J. Eugster

Quantification of vanillylmandelic acid, homovanillic acid and 5-hydroxyindoleacetic acid in urine using a dilute-and-shoot and ultra-high pressure liquid chromatography tandem mass spectrometry method

2018

Eric Grouzmann
Catherine Centeno
Philippe J. Eugster

AbstractBackground:Urinary vanillylmandelic acid (VMA) and homovanillic acid (HVA) are biomarkers for the diagnosis and follow-up of neuroblastoma, whereas urinary 5-hydroxyindoleacetic acid (5-HIAA) is used to assess a carcinoid tumor. These analytes are conventionally analyzed in a single run by c

Keywords:

Urine
5-Hydroxyindoleacetic acid
Homovanillic acid
Endocrinology
Tandem mass spectrometry
High-performance liquid chromatography
Internal medicine
Chromatography
Vanillylmandelic acid
Medicine
Vanilmandelic Acid
Neuroblastoma
Liquid chromatography–mass spectrometry

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