Legalon mastication patch and method of preparing the same

2007 
The invention discloses a silybin chewing pill and preparing method, which comprises the following parts: 10-40% silybin, 20-60% filler, 0. 01-10% acid-base modifier, 1-10% binder, 1-10% corrective and 0. 01-5% lubricant. The making method comprises the following steps: adopting organic solvent as solvent to make silybin solution to blend with binder and solution of acid-base modifier; placing fitful quantity of filler and corrective in the boiling bed to blend findings evenly; injecting the binding liquid into the findings at constant speed to grain further; drying the particle to blend with fitful quantity of lubricant evenly. The invention has good taste and high solubility of silybin to protect liver from damaging, which stimulates biological synthesis of protein in the liver cell, especially for difficultly swallowing patient or non-water intake.
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