Cyclic parathyroid hormone related protein antagonists : lysine 13 to aspartic acid 17 [i to (i + 4)] side chain to side chain lactamization

Michael Chorev,Eliahu Roubini,Roberta L. McKee,Susan W. Gibbons,Mark E. Goldman,Michael P. Caulfield,Michael Rosenblatt

Cyclic parathyroid hormone related protein antagonists : lysine 13 to aspartic acid 17 [i to (i + 4)] side chain to side chain lactamization

1991

Michael Chorev
Eliahu Roubini
Roberta L. McKee
Susan W. Gibbons
Mark E. Goldman
Michael P. Caulfield
Michael Rosenblatt

Cyclization of parathyroid hormone related protein via covalent bond formation between the ∈-amino of Lys 13 and the β-carboxyl of Asp 17 yielded a 20-membered ring lactam

Keywords:

Enzyme
Molecular biology
Side chain
Parathyroid hormone
Aspartic acid
Covalent bond
Lysine
Lactam
Biochemistry
Parathyroid hormone-related protein
Chemistry
Parathyroid hormone receptor
Cyclase
Stereochemistry
Peptide

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