Characterization of arthralgia induced by PD-1 antibody treatment in patients with metastasized cutaneous malignancies

Kristina Buder-Bakhaya,Karolina Benesova,Carsten Schulz,Hoda Anwar,Antonia Dimitrakopoulou-Strauss,Tim F. Weber,Alexander Enk,Hanns-Martin Lorenz,Jessica C. Hassel

Characterization of arthralgia induced by PD-1 antibody treatment in patients with metastasized cutaneous malignancies

2018

Kristina Buder-Bakhaya
Karolina Benesova
Carsten Schulz
Hoda Anwar
Antonia Dimitrakopoulou-Strauss
Tim F. Weber
Alexander Enk
Hanns-Martin Lorenz
Jessica C. Hassel

Background PD-1 antibodies (PD1ab) are increasingly used in metastatic melanoma and other malignancies. Arthralgia is an underestimated side effect of PD-1 antibody treatment with unknown cause. Our aim was to characterize PD1ab-induced arthralgia.

Keywords:

Immunology
Nivolumab
Melanoma
Antibody
Arthritis
Pembrolizumab
Biology
metastatic melanoma
Side effect
Dermatology
in patient

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