Preparation, structural and microstructural characterization of Ti–30Nb–10Ta–5Zr alloy for biomedical applications

Abstract Ti-30Nb-10Ta-5Zr alloy was produced and studied in the work. Plates and wires were made of this alloy. The alloy was shown to have pure β-crystalline phase and to possess the required mechanical properties. Microstructures with a height of the order of several hundred nm, located at a distance of 1.5-2.0 μm were observed on the surface of the alloy. From the point of view of reactive oxygen species generation and long-lived reactive protein species formation, the Ti-30Nb-10Ta-5Zr alloy is more preferrable than nitinol. Cultivation of cell cultures on Ti-30Nb-10Ta-5Zr surfaces resulted in high mitotic index (2%) and low content of non-viable cells (