Motoric Cognitive Risk Syndrome: Prevalence and Cognitive Performance

Introduction: Cognitive decline and dementia have a significant impact in older adults.  Motoric Cognitive Risk Syndrome (MCRS) is a pre-dementia stage where slow gait speed and subjective memory complaints are present, MCRS increase the risk of outcomes such as frailty, dementia, disability, falls and overall mortality.   Methods: Data from the SABE Colombia study (Health, Well-Being, and Aging) conducted in 2015 in community-dwelling adults aged 60 years and older. A sub-sample of 19,004 participants was obtained. Results: A prevalence of 5,45% of MCRS. After adjusting for confounding variables MCRS was associated with MMSE (OR 0·90, CI 0·82-0·99; p 0·028) and frailty (OR 9·1, CI 3·26-25·47, p 0·000; OR 21·38, CI 6·30-72·57, p 0·000). Conclusion: This study found a prevalence of 5·45% of MCRS in Colombian older adults. We found an association between cognitive performance (MMSE) and frailty with MCRS. Our results increase the awareness of a pre-dementia stages different to Mild Cognitive Impairment (MCI), as these individuals are at greater risk than those with MCI to develop dementia. Funding: The database used of this study is part of a larger project funded by the Administrative Department of Science, Technology and Innovation (Colciencias) and the Ministry of Health and Social Protection of Colombia (SABE Study 2015, ID No. 764). Declaration of Interest: None to declare.