Prophylactic budesonide nasal spray after polypectomy

This double blind study compared the effect of budesonide nasal spray with placebo, in the prophylaxis of nasal polyp recurrence after avulsion. 38 cases were given budesonide nasal spray and 25 placebo for 3 months after polypectomy. Follow up of 9 months revealed budesonide treated patients to have significantly lower recurrence rate as compared to the placebo. Interestingly patients with recurrent nasal polyposis benefitted much more from topical budesonide treatment as compared to ones with no previous history of polypectomy.