[A case of diffuse invasive hepatocellular carcinoma associated with thrombosis of the main trunk of the portal vein in which hepatic transcatheter arterial chemoembolization concomitant to the use of degradable starch microspheres (DSM-TACE) was very effective].

: The case reported here was a 80-year-old male who was presented with a diffuse type of hepatocellular carcinoma accompanied by thrombosis of the main trunk of the portal vein. The primary focus and portal vein thrombosis improved considerably following repeated transcatheter arterial chemoembolization using DSM (DSM-TACE). DSM-TACE was suggested to have the potential for becoming a new treatment method for advanced hepatocellular carcinoma, for which conventional transcatheter arterial embolization (TAE) using Lipiodol and so forth is contraindicated tue to thrombosis of the main trunk of the portal vein.