Primary adenocarcinoma of the male urethra

: We present a case of a 43-year-old man treated for urethral stricture. Cystoscopy showed unusual tissue in the posterior urethra. Biopsies showed adenocarcinoma which was positive for cytokeratins 7 and 20 and negative for prostate specific antigen. Immunohistochemistry in this case was important for the diagnosis, primary urethral adenocarcinoma.