Four-Week Repeated Intravenous Dose Toxicity of Self-Assembled-Micelle Inhibitory RNA-Targeting Amphiregulin in Mice.

Hyeon-Young Kim,Tae Rim Kim,Sunghwan Kim,In-Hyeon Kim,Je-Oh Lim,Jun-Hong Park,Sung-Il Yun,In-Chul Lee,Han-Oh Park,Jong-Choon Kim

Four-Week Repeated Intravenous Dose Toxicity of Self-Assembled-Micelle Inhibitory RNA-Targeting Amphiregulin in Mice.

2021

Hyeon-Young Kim
Tae Rim Kim
Sunghwan Kim
In-Hyeon Kim
Je-Oh Lim
Jun-Hong Park
Sung-Il Yun
In-Chul Lee
Han-Oh Park
Jong-Choon Kim

The present study investigated the potential subchronic toxicity of self-assembled-micelle inhibitory RNA-targeting amphiregulin (SAMiRNA-AREG) in mice. The test reagent was administered once-daily...

Keywords:

Pharmacology
Inhibitory postsynaptic potential
Micelle
Toxicity
intravenous dose
No-observed-adverse-effect level
Reagent
self assembled
Amphiregulin
Chemistry

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