Blood levels of primary prostaglandins along with use of Minprostin F2 alpha in the first trimester

A dose of 2.5 mg of Minprostin F2 alpha in hydroxy -cellulose gel was intracervically applied to 30 primigravidae on the eve of planned interruption. Blood samples were taken to determine prostaglandin concentrations. Rise in PG F2 alpha concentrations was recordable from peripheral venous blood of the majority of patients. - A relationship was found to exist between the extent of side effects, clinical success, and circulatory resorption of PG F2 alpha.