Regulation of ELL2 stability and polyubiquitination by EAF2 in prostate cancer cells

Tiejun Yang,Yifeng Jing,Jun Dong,Xinpei Yu,Mingming Zhong,Laura E. Pascal,Dan Wang,Zhongxian Zhang,Baoping Qiao,Zhou Wang

Regulation of ELL2 stability and polyubiquitination by EAF2 in prostate cancer cells

2018

Tiejun Yang
Yifeng Jing
Jun Dong
Xinpei Yu
Mingming Zhong
Laura E. Pascal
Dan Wang
Zhongxian Zhang
Baoping Qiao
Zhou Wang

Background: Elongation factor for RNA polymerase 2 (ELL2) and ELL associated factor 2 (EAF2) have been reported to have tumor suppressive properties in prostate epithelial cells.

Keywords:

Cancer research
Prostate cancer
Ubiquitin
Biology
Prostate
MG132
LNCaP
Gene knockdown
Cancer
Proteasome inhibitor
Immunostaining

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