Trichloro-tert.-butyl-cyclic-enediol-phosphate (TCB-CEP), Proposed Reagent for the Syntheses of Oligonucleotides Using the Triester Approach

Abstract Protected nucleosides, phosphorylated using 4, 5-dimethyl-2-oxo-2-trichloro-tert.-butyl-l, 3, λ5-dioxaphos-pholene, can be cleaved to yield either 5′- or 3′-building blocks for triester syntheses.