Contemporary outlook on prevention and correction of early disturbances of carbohydrate metabolism in cardiological practice

: In the search for effective means of prevention and detection of early markers of type 2 diabetes mellitus (DM) the scientists take an interest for early disturbances of carbohydrate metabolism. In this work we present data of international clinical studies confirming that early disturbances of carbohydrate metabolism appear to be an independent risk factor of cardiovascular diseases. In this connection possibilities of prevention and treatment of early disturbances of carbohydrate metabolism are discussed. We also present classification of antihyperglycemic drugs and analysis of their mechanism of action and efficacy from the point of view of evidence based medicine. The data presented evidence that successful primary prevention of type 2 DM at the stage of early disturbances of carbohydrate metabolism can facilitate lowering of cardiovascular complications.