Simulating the effect of cerebral blood flow changes on regional quantification of [18F]flutemetamol and [18F]florbetaben studies.

Fiona Heeman,Maqsood Yaqub,Isadora Lopes Alves,Kerstin Heurling,Santiago Bullich,Juan Domingo Gispert,Ronald Boellaard,Adriaan A. Lammertsma

Simulating the effect of cerebral blood flow changes on regional quantification of [18F]flutemetamol and [18F]florbetaben studies.

2020

Fiona Heeman
Maqsood Yaqub
Isadora Lopes Alves
Kerstin Heurling
Santiago Bullich
Juan Domingo Gispert
Ronald Boellaard
Adriaan A. Lammertsma

Global and regional changes in cerebral blood flow (CBF) can result in biased quantitative estimates of amyloid load by PET imaging. Therefore, the current simulation study assessed effects of thes...

Keywords:

Diabetes mellitus
Anesthesia
18F-florbetaben
Cerebral blood flow
Biology
Amyloid
amyloid pet
pet imaging
Cardiology
Internal medicine

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