The relationship between ideal cardiovascular health behaviors and factors with serum uric acid

Objective To investigate the effects of ideal cardiovascular health behaviors and factors(ICHBF)on the levels of serum uric acid(UA). Methods The Kailuan staff who participated in the 2006-2007 health examination were investigated with a cross-sectional study method. In total,95 332subjects(76 044 males,aged 52.1±12.6years old and 19 288 females,aged 48.7±11.5years old),with complete data on serum UA and cardiovascular health behaviors and factors were finally recruited. Questionnaires and blood biochemical examinations were carried out for all subjects. According to the American Heart Association(AHA)definition of ICHBF,multivariate Logistic regression analysis was used to assess the effects of ICHBF on the levels of serum UA. Results With the increasing number of ICHBF,serum UA levels in both males and females exhibited a declined tendency,with significant differences observed in both groups. Multiple Logistic regression analysis revealed that the risk for hyperuricemia(HUA)was reduced gradually with the increasing number of ICHBF. Further,in both genders,the risk for HUA was declined with the increase of ICHBF(2,3,4and≥5),compared with the subjects who had none or only one ICHBF,with the corresponding odds ratios of being 0.95(95%confidence interval:0.75-1.22),0.76(0.60-0.97),0.69(0.53-0.89),0.63(0.48-0.84)in females and 0.86(0.79-0.93),0.69(0.64-0.75),0.57(0.52-0.63),0.62(0.54-0.71)in males,respectively,after adjusting for age,educational level,alcohol drinking,income,triglyceride,low density lipoprotein cholesterol,high density lipoprotein cholesterol,creatinine and high-sensitive C-reactive protein. Conclusion With the increasing number of ICHBF,the risk of HUA reduces gradually.