Transcatheter tricuspid valve implantation: a multicentre French study.

Summary Background Transcatheter valve-in-valve (VIV) implantation in failing bioprosthesis is an emerging field in cardiology. Aim To report on a French multicentre experience and a literature review of tricuspid VIV implantation. Methods We approached different institutions and collected 10 unpublished cases; a literature review identified 71 patients, including our 10 cases. Clinical aspects and haemodynamic data are discussed. Results Among our 10 unpublished cases, the reason for implantation was significant tricuspid stenosis ( n  = 4), significant tricuspid regurgitation ( n  = 1) or mixed lesion ( n  = 5). Implantation was performed under general anaesthesia at mean age 28 ± 17 years. The 22 mm Melody valve was implanted in seven patients; the Edwards SAPIEN valve was implanted in three patients. The procedure succeeded in all cases, despite two embolizations in the right cardiac chambers; in both cases, the valve was stabilized close to the tricuspid annulus using a self-expandable stent, before implantation of a second Edwards SAPIEN valve. Functional class improved in all but one case. Mean diastolic gradient decreased from 9 ± 2.45 mmHg to 3.65 ± 0.7 mmHg ( p  = 0.007); no more than trivial regurgitation was noticed. Among the published cases, the Melody valve was implanted in 41 patients, the Edwards SAPIEN valve in 29 patients and the Braile valve in one patient. Short-term results were similar for our 10 cases, but mid-term results are not yet available. Conclusions Tricuspid VIV implantation using the Melody or Edwards SAPIEN valves is a feasible and effective procedure for selected patients with failing bioprosthesis.