Efficacy of one dose fluoroquinolone before prostate biopsy

Abstract Objectives. To demonstrate the efficacy of a simple preparation for prostate biopsy (PBX) and to determine its potential cost savings. Methods. One hundred fifty consecutive PBXs were performed using a Fleet enema and a single oral dose (300 mg) of ofloxacin as the pre-PBX preparation. Results. Of the 150 PBXs we performed, only 1 (0.67%) patient developed a urinary tract infection. Conclusions. A simple and inexpensive pre-PBX preparation proved to be successful in preventing infectious complications and is presented as a potential model for inclusion in clinical pathways for diagnosing adenocarcinoma of the prostate.