Valuable insights from real-life experiences of advanced thyroid cancer treatment with sorafenib in Latin America.

Approximately 10,000 new cases of thyroid cancer are diagnosed annually in Brazil (), most of the cases are associated with a survival rate of over 98% 5 years after diagnosis, but 10-20% present or eventually develop distant metastases (,). Until recently, the only effective treatment for distant metastatic disease was radioactive iodine (RAI) and the prognosis of patients who failed RAI therapy was poor, the 10-yr survival rate being only 10% (). From these, patients with enlarging and FDG-PET positive [...]