Effects of Parenterally Administered Ciprofloxacin in a Murine Model of Pulmonary Pseudomonas aeruginosa Infection Mimicking Ventilator-Associated Pneumonia

Yukihiro Kaneko,Katsunori Yanagihara,Misuzu Kuroki,Hideo Ohi,Hiroshi Kakeya,Yoshitsugu Miyazaki,Yasuhito Higashiyama,Yoichi Hirakata,Kazunori Tomono,Jun-ichi Kadota,Shigeru Kohno

Effects of Parenterally Administered Ciprofloxacin in a Murine Model of Pulmonary Pseudomonas aeruginosa Infection Mimicking Ventilator-Associated Pneumonia

2001

Yukihiro Kaneko
Katsunori Yanagihara
Misuzu Kuroki
Hideo Ohi
Hiroshi Kakeya
Yoshitsugu Miyazaki
Yasuhito Higashiyama
Yoichi Hirakata
Kazunori Tomono
Jun-ichi Kadota
Shigeru Kohno

Background and Methods: We compared the bacteriological, pharmacological and histopathological effects of parenterally administered ciprofloxacin (CPFX) to those of imipenem/cilasta

Keywords:

Microbiology
Respiratory disease
Ciprofloxacin
Cilastatin
Imipenem
Antibiotics
Ventilator-associated pneumonia
Minimum inhibitory concentration
Medicine
Pseudomonas aeruginosa
antibacterial agent

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