Sensitivity and specificity of an oral uracil-loading test dose for screening for DPD deficiency.
2014
11101 Background: 5-fluorouracil (5FU) and capecitabine (CAP) are extensively metabolised by dihydropyrimidine dehydrogenase (DPD). DPD deficiency can lead to severe toxicity after 5FU or CAP. Urac...
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