Zur Pathogenese des Urämiesyndroms. Brenztraubensäure, Acetoin und 2,3-Butylenglykol in Blut von Patienten mit Nieren- und Leberkrankheiten

Acetoin and 2, 3-butylene glycol in blood of renal and hepatic patients are raised, when consciousness is disturbed. There is no correlation between blood levels of acetoin and 2, 3-butylene glycol and the degree of impairment of consciousness. Simultaneous determinations of acetoin and 2, 3-butylene glycol in blood and cerebrospinal fluid show that alterations of the cerebral pyruvic acid metabolism are difficult to detect in circulating blood.