EVALUATION OF PHYTOCHEMICALS AND IN VITRO ANTI-DIABETIC, ANTIINFLAMMATORY ACTIVITY OF Ruellia prostrata LEAVES EXTRACT

Medicinal plants are important in the treatment of human diseases. Phytochemicals that possess anti-diabetic and anti-inflammatory activity, and modulate pathways involved in obesity and glucose metabolism. In folk medicine, a single plant may be used to treat various diseases owing to the presence of phytochemical varieties in plants. The qualitative analysis showed that the preliminary phytochemical analysis of Ruellia prostrata revealed presence of tannin, saponins, flavonoids, steroids, terpenoids, triterpenoids, anthroquinones and polyphenol while emodins, anthocyanins were absent in both extract. Alkaloids and glycosides were present only ethanol extract. Coumarins were present only aqueous extract. . The in vitro anti-diabetic potential of plant extract was confirmed through α-amylase and α-glucosidase inhibition methods. Anti-inflammatory activity of Ruellia prostrata was also confirmed.