METASTASIS OF RENAL CELL CARCINOMA TO MAXILLARY GINGIVA: A CASE REPORT

A 63-year-old white male presented with maxillary gingival swelling for a 6-month duration. Medical history revealed diabetes and hypertension. Extraoral examination was noncontributory. Intraoral exam showed a red bleeding lobulated nodule measuring 5.0 × 3.0 cm in the left maxillary gingiva. The presumptive diagnosis was nonneoplastic reactive lesion. An incisional biopsy was performed and histopathologic diagnosis was unspecific malignant neoplasm. The initial immunohistochemical panel was inconclusive. The panoramic radiography showed extensive bone destruction in the left maxilla. Abdominal and chest computed tomography (CT) revealed lesions in the liver, kidney, and lung. Magnetic resonance imaging (MRI) of the central nervous system (CNS) showed nodules in left parietal lobe. An ultrasound-guided biopsy of the right kidney confirmed the diagnosis of clear cell renal carcinoma, with metastasis to the liver, lung, CNS, and oral cavity. The treatment combined surgery, palliative chemotherapy, and radiotherapy with partial remission of the lesions. The patient remains under treatment.