Quantitative study of the cerebral hemodynamics by using multislice CT perfusion imaging in normal adult

2008 
Objective:To explore the application value of multislice CT perfusion imaging in normal adult cerebral hemodynamics. Methods:Routine CT and multislice CT perfusion imaging were performed by selecting the basal ganglia slice and its adjacent slice in 24 normal adults,These scan dynamic images were peocessed with the CT perfusion software package.Cerebral blood flow(CBF),cerebral blood volume(CBV) and mean transiting time(MTT) were measured within the specific regions of interest(ROI) of the brain,and quantitative analysis was performed. Results:A gradient of perfusion between gray matter and white matter showed on multislice CT perfusion imaging in normal adults.CBF,CBV,MTT were(52.8±10.0)ml/(100g·min),(2.7±0.6)ml/100g,(3.7±0.9)s respedtively in the gray matter and(22.0±3.3)ml/(100g·min),(1.3±0.4)ml/100g,(5±1.2)s respectively in the white matter. Conclusion:multislice CT perfusion imaging provided a new imaging method for measuring the cerebral hemodynamics.
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