A tri-metallic palladium complex with breast cancer stem cell potency

Arvin Eskandari,Arunangshu Kundu,Alice Johnson,Sanjib Karmakar,Sushobhan Ghosh,Kogularamanan Suntharalingam

A tri-metallic palladium complex with breast cancer stem cell potency

2020

Arvin Eskandari
Arunangshu Kundu
Alice Johnson
Sanjib Karmakar
Sushobhan Ghosh
Kogularamanan Suntharalingam

A multi-nuclear, triangular-shaped palladium(II) complex is shown to equipotently kill bulk cancer cells and cancer stem cells (CSCs) in the micromolar range. The palladium(II) complex evokes CSC apoptosis by entering CSC nuclei and damaging genomic DNA.

Keywords:

Cancer stem cell
Cancer research
Cancer cell
genomic DNA
Photochemistry
Potency
Chemistry
breast cancer stem cell
Metal
Apoptosis
Palladium

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