P-182 Examination of Crohnʼs Disease Variants in a Fraternal Twin Family Using Exome Sequencing and Inflammatory Bowel Disease-Associated Single Nucleotide Polymorphisms

Background:A unique opportunity for genetic investigation was presented by a 3-generation family with fraternal twins, one of whom had Crohn's disease (CD) with 2 affected children and the other who was healthy with 3 unaffected children, suggesting an autosomal dominant inheritance. This study test