Method for producing a pluripotent stem cell

According to the present invention, in a time of producing a cell population containing a pluripotent stem cell, treating the somatic cells contacted with nuclear reprogramming factors in drug to arrest processes, and / or cell cycle treated with starvation conditions the inclusion of the step of. Thus, induced pluripotent stem cells at high frequency, it is possible to grow, it is possible to produce pluripotent stem cells with high efficiency. The said nuclear reprogramming factor, for example, OCT4, SOX2, c-MYC, KLF4, NANOG and nuclear reprogramming factor selected from the group consisting of LIN28 can be used.