[Pertussis trend in children under one year of age in the Czech Republic in 1997-2013 Study objective: To characterize the epidemiological situation of pertussis in children under one year of age in the Czech Republic in 1997-2013]

Material and methods: The study cohort consisted of children under one year of age with laboratory confirmed pertussis reported to the communicable disease system from 1997 to 2013. A total of 265 pertussis cases were reported in children under one year of age over the study period. Selected demographic data need for hospitalization and vaccination history were evaluated in the study cohort. Results: Children under one year of age have shown a steady upward trend in reported cases of pertussis since the 1990s. The reported incidence of pertussis in this age group was the lowest in 1998 (1.1/100 000 population) and the highest in 2013 (31.3/100 000). In 1997-2013 265 pertussis cases were reported in children under one year of age 128 females and 137 males to the communicable disease system in the Czech Republic. Most of these children nearly 77% developed pertussis within the first four months of life. Of the 265 children 79% were not vaccinated before the onset of the disease and 21% were immunized with at least one dose of pertussis vaccine before developing the disease. As many as 75% of the children with pertussis needed hospitalization. Most of them nearly 81% were hospitalized with pertussis in the first four months of life and 90% of them in the first six months of life. Conclusions: In 1997 – 2013 an upward trend was observed in pertussis cases in children under one year of age. Most children developed the disease within the first four months of life while not vaccinated against pertussis. This fact unambiguously supports the „cocoon“strategy i.e. vaccination of the closest contacts of the child and a booster dose at 25 years of age. At the same time a question arises whether to provide vaccination to pregnant women.