The combination of synergistic agent containing roflumilast and pde-3 inhibitors

(57) Abstract: The present invention, certain disease states, for example, for treating acute or chronic bronchial obstruction, PDE3 inhibitors and PDE4 inhibitors N-(3,5-dichloropyrid-4-yl) -3- cyclopropylmethoxy-4-difluoromethoxy benzamide relates to the combination use with a pharmacologically acceptable salt or N- oxide.