Performance of combined OCT/MFI microendoscope for ovarian cancer detection

To improve early detection of ovarian cancer, we have designed and built a microendoscope that combines optical coherence tomography (OCT) and multispectral fluorescence imaging (MFI) into a 0.7 mm diameter package. An endoscope of this size allows access to the ovaries through the fallopian tubes creating a minimally invasive procedure. We characterize the falloposcope’s imaging behavior and show that this system provides contrast on ex vivo surgical samples of ovary and fallopian tube. In addition, we show the mechanical performance of the endoscope in an anatomically correct model of the female reproductive treatment.