Toxic epidermal necrolysis and co-existent SARS-CoV-2 (COVID-19) treated with Intravenous Immunoglobulin: "Killing 2 birds with one stone".

2020 
Toxic Epidermal Necrolysis (TEN) is classified as severe cutaneous adverse reaction. It can be induced by drugs, infection, and malignancy or can be idiopathic. We present a 62-year-old male of Indian origin with a widespread, tender, erythematous maculo-papular eruption and targetoid lesions on the palms and soles. He had a history of multiple myeloma and a stem cell transplant in 2008. He was recently started on amoxicillin for a suspected lower respiratory tract infection and lenalidomide, septrin and allopurinol 6 weeks prior to presentation due to a relapse of the myeloma. The rash evolved into large areas of flaccid blistering (over 30% of the body surface area) with severe mucosal involvement (Fig.1a) and a diagnosis of TEN was made.
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