Premature Ventricular Complex Site of Origin and Ablation Outcomes in Patients with Prior Myocardial Infarction.

ABSTRACT Background Frequent premature ventricular complexes (PVCs) are common after a myocardial infarction (MI), but data on PVC ablation in this population is limited. Objective To analyze data on PVC ablation in post-MI patients. Methods 332 patients with frequent PVC and left ventricular (LV) dysfunction were prospectively included. Data from 67 (20%) patients [63±10 years old, 65 (93%) men] with previous MI were compared with the remaining 265 patients. Results PVCs in post-MI patients originate predominantly from the LV [92% LV vs 6% right ventricle (RV), p Conclusion PVC ablation significantly improves cardiac function and functional status in post-MI patients. PVCs predominantly originate from the MI scar and LVOT. A papillary muscle SOO was found to be strongly associated to the presence of a previous MI.