Appearance of an entodermal antigen in the oral mucosa of dogs with recurrent spontaneous stomatitis

In dogs with stomatitis an additional component appears in the mucous membrane, of the cheeks, tongue, and hard palate (ectodermal derivatives), which is not found in the homonymous areas of the normal oral mucosa. The component discovered was completely identical immunochemically with antigens of the mucous membrane of the soft palate, esophagus, stomach, and large and small intestines, which are entodermal derivatives. In other organs and tissues studied no entodermal antigen was found.