Abstract 19133: Diabetes is associated With Unrecognized Myocardial Infarctions in African-Americans: The Jackson Heart Study

Background: Almost 1/2 of initial myocardial infarctions (MI) are unrecognized or clinically-silent (UMI), which forecasts future clinical events. While diabetes mellitus (DM) increases the risk for UMI, few studies regarding impaired fasting glucose (IFG) as a risk factor for UMI exist. Further, limited data exists to describe the potential risk for UMI in African-Americans. Methods: The relationship of glucose status with UMI was examined in the Jackson Heart Study: a cohort of African-American individuals. At baseline, there were 5,073 participants who had an initial 12-lead electrocardiogram (ECG) and fasting glucose measured. Of these participants, 106 (2.1%) had an UMI, and 268 (4.2%) had a known MI. This population consisted of 3,348 participants with normal fasting glucose (NFG), 573 with IFG, and 1,152 with DM. NFG had a fasting glucose level 125 mg/dl or a diagnosis of DM. Crude and adjusted odds ratios (HRs) were calculated to dete...