ERK phosphorylation and miR-181a expression modulate activation of human memory T H 17 cells
2015
How the magnitude of the response is regulated in different T-cell memory subsets remains poorly understood. Here the authors show that miR-181 lowers the threshold of Th17 memory activation via sustained Erk phosphorylation, while Erk-dependent induction of ID3 limits Th17 activity at later time.
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