Diffusion Tensor Imaging and Fiber Tractography in Syntelencephaly

Syntelencephaly or the middle interhemispheric variant of holoprosencephaly is a rare subtype of holoprosencephaly and consists of a nonseparation of the posterior frontal and parietal regions of both cerebral hemispheres. We report conventional MR imaging, diffusion tensor imaging, and fiber tractography findings of a girl with syntelencephaly and discuss the information that diffusion tensor imaging and fiber tractography may add to conventional MR imaging in this rare brain malformation.