D-galactose/benzaldehyde nitrogen mustard/N-(2-hydroxypropyl) methacrylamide copolymer as well as preparation and application thereof

The invention provides a D-galactose/benzaldehyde nitrogen mustard/N-(2-hydroxypropyl) methacrylamide copolymer, and belongs to the field of high polymer chemistry and application. The D-galactose/benzaldehyde nitrogen mustard/N-(2-hydroxypropyl) methacrylamide copolymer is a macromolecular copolymer which has good biocompatibility and is formed in the way that D-galactose and benzaldehyde nitrogen mustard are linked to N-(2-hydroxypropyl) methacrylamide (HPMA) through covalent bonds. An experiment proves that the D-galactose/benzaldehyde nitrogen mustard/N-(2-hydroxypropyl) methacrylamide copolymer has the function of intelligently releasing drugs in a targeting manner, and has excellent inhibiting effect on a liver cancer HepG2 tumor cell; besides the macromolecular copolymer is an effective drug delivery system; therefore, the copolymer has excellent prospect as being used as an inhibitor for the HepG2 tumor cell and the like to be applied to the preparation of anti-tumor drugs.