Initial clinical experiences with the photodynamic therapy (PDT) of oral cavity carcinomas

: Photodynamic therapy (PDT) is based on the selective accumulation of photosensitizing agents in tumor tissues. Activation of the photosensitizer with ligh of suitable wavelength leads to tumor destruction preserving healthy tissues. 13 carcinomas stage T1 and T2 of the oral cavity in men were treated. Necroses of a depth from 1.5 to 6 mm occurred regularly. Therefore photodynamic therapy seems to be suitable to treat small, superficial cancers of the oral cavity, especially, if the tumors are multilocated.