Targeting siglec-E on murine dendritic cells inhibits antigen presentation and CD4 and CD8 t cell responses

Dendritic cells (DCs) are the most potent antigen presenting cells of the immune system. They are important regulators of immune responses by their capacity to induce tolerance or immunity, depending on the type of antigen they encounter with their cell surface receptors. An important group of cell surface receptors expressed by DCs are …