Study on chemical constitutes of {\sl Codonopsis pilosula}

OBJECTIVE To elucidate the active component for the quality evaluation of Rdix Codonopsis.METHODS The compounds were separated with chromatography techniques and their structures were elucidated on the basis of spectroscopic evidences and physiochemical properties. RESULTS Ten compounds were isolated from the n-butanol fraction of the ethanolic extract of Codonopsis pilosula and structurally identified as lobetyolin (1),syringin (2), hexyl-β-D-glucopyrannoside (3), butyl-β-D-fructofurnanoside (4), lobetyolinin (5), geniposide (6), tryptophan (7), uracil (8),3',4',5,9,9'- pentaydroxy-5-4,7' -epoxylignan (9) and emodin (10) , respectively. CONCLUSION Compound 4-10 are isolated from genus Codonopsis for the first time and lobetyolin (Ⅰ) can be chosen for quality evaluation.